Acta Scientific Women's Health
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Population Control and Women Health
Asian, African, South American and other poor regions of the globe are being extremely overcrowded due to high population growth rate and the material resources of these regions are being choked, which ultimately affects the quality of life for the masses of these regions and is also affecting the health and life span of women of these regions. More than 50 per cent population of these regions does not have basic facilities like potable water, basic edu-cation, proper health facilities, proper, decent and suitable housing, decent clothing and nutritional food. The living standards of the people of these regions are very poor and majority of them lives below the poverty line.
The Role of Radiologist in Conservative Management of Breast Cancer
Tarek Aref1 and Walid Mohamed Ahmed
Breast conserving therapy (BCT) means breast conserving surgery (BCS), followed by a suitable-dose of radiotherapy to eliminate any microscopic residual neoplastic breast disease. BCS is currently considered the most suitable protocol for management of early stage of invasive cancer, that combines both adequate surgical margins and an acceptable cosmetic result. The role of mammography and breast ultrasonography for many years was concerning the diagnosis of breast tumors and local recurrence after treatment. The advent of the Breast Imaging Reporting and Data System (BIRADS) by the American College of Radiology, helps to maximize Radiolo-gist’s role through any factors: standardized the description and recommended management of breast lesions. BIRADS has increased the radiopathological correlation of radiologists’ reports, improving the reports’ reliability and has also established a common lan-guage for all of the physicians involved in multidisciplinary breast disease management team, favoring agreement on decisions, and Furthermore, advances in breast magnetic resonance imaging; functional MRI and image-guided interventional procedures have increased our responsibility in the therapeutic decision-making process. The role of Radiologist in BCT: I- Accurate and early diag-nosis of breast cancer and staging. II- Interventional role of Radiologist in BCT including imaging-guided biopsy of breast masses, stereotactic biopsy of nonpalpable lesions and or microcalcifications guided by mammography or MRI. Post-biopsy-clips insertion, and pre-neoadjuvant chemotherapy localization of malignant lesion by US-guided insertion of a hydromark (clips). Pre-operative localization of non-palpable breast mass or microcalcifications by US-guided insertion of wire. III- Evaluation of response to neoad-juvant therapy using RECIST (Response Evaluation Criteria in Solid Tumors).
Assessment on Frequency of ABO Blood Group and RH (D) Negative Mothers among Pregnant Women Attending at Antenatal Care Clinic of Sodo Health Center, SNNPR, Ethiopia
It's important for women to find out their blood type at the start of their pregnancy. Blood will be taken to find out and there are four different types: A, B, AB and O.In addition to blood type, women can have Rh factor (specifically Rhesus D antigen), which is when proteins appear on the surface of the blood. Women who do have Rh factor are classified as Rh positive (A+, B+, AB+ and O+) and women who don't are Rh negative (A-, B-, AB- and O).
Effect of Endosulfan Toxicity on 1st Stage of Spermiogenesis Leading to Infertility
Asiya Nisa, Yashowardhan Suman, Mehjabeen1 and Suhail Jeelani Shah
Toxicities of organochlorine pesticides like Endosulfan show adverse effects on many organs and organ systems like liver, kid-ney, testes, muscles, immune system and hematological system. Most of the previous studies focused on effects of organochlorine on activity of spermatogenic cells. However, there is very little research reporting effects of endosulfan on spermiogenesis till date. Therefore, the current study was aimed to assess the effect of Endosulfan on spermiogenesis in the testes of mice model. A 5 mg/gm body wt. Endosulfan was administered to mice by oral gavage method. Normally in the beginning of spermiogenesis, the sperm head gets embedded in the sertoli cell and finally released from the seminiferous tubules. It is very significant to note that the testes in endosulfan treated mice. They were found to get affected at an early stage (from spermatids to 1st stage of spermiogenesis), as com-pared to any other organochlorine pesticide. The present study also confirms that only oral administration (5 mg/gm body wt.) for 20 days shows effect on spermiogenesis in 30% of mice. Furthermore, in 20 days treated mice, notable changes were seen during the 1st stage of spermiogenesis. Significant decrease in testosterone level (P ≤ 0.0001) and sperm count (P ≤ 0.001) was observed after endosulfan exposure. Abnormal spermatozoa in the lumen of seminiferous tubules were found to be very few in number and with a non-motile tail. Approximately 30% of the heads of spermatozoa were found with rounded acrosome, which will lead to infertility.
Currently Used Drugs for Prevention and Treatment of Acute Organ Rejection
Vera Maravić-Stojković and Branislav Stojković
It is clear from the knowledge gained from the ancient times that healing is not as simple process as it seems. During long periods of time, major advancements in technology, pharmacology, and medicine have enabled the extraction of countless remedial prod-ucts from the plants. And not only from plants. Natural products have also been extracted from animal organs and later, synthetic equivalents with identical properties have been developed. The fascinating progress of humankind was achieved when the animal organs have become available as a drug. Nevertheless, revolutionary progress in solid organ transplantation was marked by the in-troduction of the cyclosporine A. Transplant immunology has become a leading science in modern medicine. Since then, solid organ transplantation has become a routine procedure accomplished with the help of protocols of immunosuppressive therapy. This article is designed as an overview of currently used immunosuppression in solid organ transplantation. Currently available groups: steroids, antimetabolites, polyclonal and monoclonal antibodies, calcineurin inhibitors, proliferation signal inhibitors, are described closely below. Each transplant center creates their own protocols. Protocols for immunosuppressive therapy offer three major strategies: in-duction, maintenance and therapy for treating acute rejection. The backbone of immunosuppression in organ transplantation recipi-ent: cyclosporine A and tacrolimus, have been widely used as maintenance therapy combined with adjunctive immunosuppressant. These drugs are in use either as a prophylaxis or as the part of the maintenance immunosuppressive treatment. Induction therapy provides immunologic ablation with upstream antibody therapy as prelude to induce graft tolerance. Protocols are briefly described in the text
Extramarital Affairs (EMA) for Indian Women: An Overview of its Health Impacts
Extramarital affairs (EMA) of men and women is becoming a rising Phenomenon in our modern society globally. Both men and women may get sexual and/or emotional motivations for EMA if their marriage is not satisfying in any aspect. EMA can put serious Impact on women if it is not secret. So, Couples should openly communicate regarding their sexual desires and expectations in their Married relationship to their partners
Effect of Data Selection on Reimbursement Decisions. Breast Cancer Case
One of the daily challenges for health care policy makers is selecting the right patient for the right treatment with affordable price. If we taking breast cancer treatments at law middle income country, as Egypt's experience with breast cancer, an incidence (15.4) per 100,000 beside the prevalence of HER2-positive breast cancer is approximately 15% to 20% of primary breast cancers. this will lead to economic burden as well as consequences on decision makers. When they decides to treat with monoclonal antibodies like Trastuzumab what is the appropriate time to treat the patient to achieve the efficient management of resources 6 months versus 12 months of adjuvant Trastuzumab in early breast cancer. What will be the best option for the resources and patients outcomes?To answer the previous question an economic study was conducted trying to support decisions makers. The result of economic model showed that selecting one clinical study for deciding shorter time regimen versus standard regimen is might not be strong evidence for taking the decisions because the economic model was so sensitive to the following parameters. Selecting data for health care decision making in oncology should take in consideration.Strength of evidence sensitivity analysis of that data should be conducted to ensure effective health care decisions and losing the previous criteria might lead to negative impact on patients’ outcomes and treatment resources.
Knowledge Attitude and Practice of Health Care Workers towards COVID-19 in Nowshera Pakistan
Corona Virus disease termed as COVID-19, is an emerging highly contagious respiratory disease that is caused by novel corona virus. It was first reported from Wuhan China in December 2019.
An Observational Study of Women’s Experience and Health Needs Related to Menopause at the Clinic of complementary medicine in Lucca, Tuscany Region,Italy
Introduction During their life women go through very different phases such as puberty, fertile age, pregnancy, puerperium and menopause. Each phase is defined by important changes and different women’s needs. In particular, menopause determining the end of the fertile age, represents a delicate period which although can be experienced in very subjective way, is generally characterised by a higher psycho-physical vulnerability.
DIY Making an Herbal Extract and High-Tannic Wine Treated Nose-Filter against Coronavirus
Johnson K Gao
This article is based on the current situation that the sudden explosion of coronavirus epidemic causes a shortage of facemask. It is known that Dryopteris root, Radix isatidis have antiviral effect. Tannic acid can fix the cell membrane in electron microscopy sample preparation. Tannic acid could also cause certain degree of fixation or alteration of coronavirus membrane. The Domaine de Moulie red wine is famous in its source of Tannat grapes, which contains higher concentration of tannic acid. This is a suggestion to use Domaine de Moulie red wine to extract antiviral chemicals from herbs to treat gauze, and then use that kind of gauze to make a nose filter in order to decrease the possibility of transmission of coronavirus. However, the effectiveness has not yet been validated
Effect of Soy Beans on Women Health
Soybean contains all amino acid essential to human beings and has a positive effect on health. It is widely available in India and many studies reported the positive effects of soybeans. Ingestion of soybeans may help to prevent and control chronic diseases such as diabetes mellitus, cancer and improve the quality of life in postmenupausal women.
Novel Coronavirus Disease (COVID-19): Pregnancy Issues
Goce Kalcev;Ivan Barbov ; Jovan Bozinovski and Elizabeta Zisovska
Immune and physiological changes that occur during a woman's pregnancy place her in a high-risk group for the physical and mental health consequences of various factors . Previous studies showed high rates of maternal mortality, abortion, and preterm labor after pneumonia caused by the H1N1, MERS, influenza A, and SARS viruses . However, information on the impact of COVID-19 infection on mothers and newborns outcomes is veru limited.
Endometriosis in Umbilical Hernia
Saud Al Omani and Nouf Yassin
Endometriosis is the presence of functional endometrium tissue outside the uterus. It affects approximately 11% of the population . Here we present a patient with atypicalhistory who was found to have Extra-pelvic endometerosisin the sac of a recurrent para-umbelical hernia