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American Journal of Biomedical Science & Research

ISSN(p): | ISSN(e):2642-1747
Journal Papers (24) Details
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Indexed Journal

1 Thiamine Deficiency and Benfotiamine Therapy in Brain Diseases , Dragan M Pavlović
Thiamine is hydrosoluble molecule from B vitamins family vitamin that is crucial for the metabolism of glucose and is essential for the normal growth and development of the organism, as well as for the normal function of body systems such as digestive, cardiovascular and nervous system, both central (CNS) and peripheral (PNS), and also stimulates the brain and improves the psycho-emotional state. Hypovitaminosis B1 is more common than it is thought, primarily due to the discrepancy in high intake of pure calories and the low intake of vitamins. The most frequent deficiencies of thiamine are Wernicke’s encephalopathy, Korsakoff’s psychosis, beriberi, Alzheimer’s disease, but many more cases are those of marginal deficit of thiamine. Benfotiamine is a synthetic vitamin B1 that is liposoluble than manifold increases his penetration in brain and peripheral nerves compared to thiamine. Benfotiamine is thiamine precursor that can be converted into thiamine in tissues and then metabolites into thiamine monophosphate and thiamine diphosphate. Polyphenols in coffee and tea can inactivate thiamine.The effects of benfotiamine are mild inhibition of cholinesterase, reduction in production of amyloid plaques and hyperphosphorylated tau. Benfotiamine inhibits the three main pathways leading to hyperglycemic damage. Long-term administration of benfotiamine corrects cognitive status. Usual doses of benfotiamine are 150 mg or 300 mg once or twice daily. In some cases, Korsakoff psychosis requires long-term administration of benfotiamine in maintenance dose with excellent results.
2 Alcohol Consumption Prevention Strategies , Lídia Susana Mendes
The alcohol consumption affects an increasing number of people around the world, and an estimated 2.3 million over the age of 15 are consuming alcoholic beverages [1]. Binge drinking (BD) is a consumption over 60 gr or more of pure alcohol in one occasion at least one time in the last month, affects young people (15-19 years), with a peak at 20-24 years [1].There are multiple factors of vulnerability associated with alcohol consumption. The choice of the drink and the age at which the consumptions occur result from the combination of both individual and social vulnerability. The Individual factors that condition alcohol consumption is age, gender, family conditions, religious affiliation, and socioeconomic status (WHO 2014; Collins, 2016). Other conditions, of society, such as the level of development, culture, context of consumption and production of alcohol, distribution and regulation, also have an influence in the consumption of alcoholic beverages.
3 Phosphatidylethanol (PEth); the Superior Direct Alcohol Biomarker against Mean Corpuscular Volume (MCV), Aspartate Amino Transferase (AST), Alanine Aminotransferase (ALT), Gamma-Glutamyl Transferase (GGT) and Carbohydrate-Deficient Transferrin (CDT) , Salah Eddine Breidi
As ethanol itself is metabolised and excreted quickly from the body, assessing alcohol consumption with a blood test relies on other markers indicative of consumption. Traditional tests include Liver Function Testing (LFT), Carbohydrate Deficient Transferrin (CDT) Testing, and a Full Blood Count (FBC). Phosphatidylethanol (PEth) testing, on the other hand, is a direct biomarker of alcohol consumption, can only be detected when alcohol has been consumed, and is directly correlated with the level of alcohol consumed.
4 Improving Sleep with the Unique and the Newly Developed Acupoint Protocol to Fight Against Cancer Pain , Tony Hong
Pain is a very common condition which can affect the quality of life of patients at any time. Rated from a dull ache to a sharp stab and ranged from mild to server in the daily life, pain management is attracting more and more attention because the occurrence of pain rises when people are getting older. Compared to men, women are more likely to experience pain which is generally classified into acute pain which is understood to be the normal response to tissue injury, and chronic (ongoing) pain that persists beyond the normal time of healing and generally lasts for more than three months [1].
5 CDC Alert for Hospital Infections due to Candida Auris Multiresistant , Dra Mirta D Ambra
The Centers for Disease Control and Prevention (CDC) has received reports from international health centers that Candida auris multi-drug resistant yeast is causing health-associated invasive infections with high mortality. Some strains of C. auris have high minimum inhibitory concentrations (MIC) to the three main classes of antifungals, severely limiting treatment options. C. auris requires specialized methods for its identification and could be mistakenly identified as another yeast when the procedure is based on traditional biochemical methods. The CDC is aware that a strain of C. auris was detected in the United States in 2013 as part of ongoing surveillance. The experience outside the United States suggests that C. auris has a high potential to cause outbreaks in health centers. Given the presence of C. auris in nine countries on four continents since 2009, the CDC is alerting health centers in the United States to be on the lookout for C. auris infections in patients.
6 The Coexistence of Hypertension and Dyslipidemia in a Cohort of Iraqi patients with essential Hypertension: Cross Sectional Study , Ali Fawzi Abdalsahib Al Zamili
Hypertension and hyperlipidemia are among major risk factors for ischemic heart disease, the principal human killer worldwide. In addition, they form important components of the well-established metabolic syndrome. Generally speaking, dyslipidemia comprises abnormality in the level of triglyceride, HDL-cholesterol and LDL-cholesterol. The description of hypertension and dyslipidemia as a single entity under the title “dyslipidemic hypertension (DH)” has emerged in medical literatures since 1988; a suggestion was made at that time as being a genetic syndrome to explain the coexistence of dyslipidemia and essential hypertension in a subset of patients.
7 Sino-nasal T/NK lymphomas (Medio-Facial Malignant Granulomas) , Jbali Souheil
Nasal T / NK Lymphoma Was First Described In 1933 As A Medio-Facial Malignant Granuloma. The Diagnosis of This Rare Disease Is Clinical and Immuno-Histopathological. We Report 18 Cases of TNK Lymphoma Collected at ENT and Maxillo-Facial Surgery Department Of La Rabta Hospital Over A Period Of 17 Years (2000-2016). We Included in This Work All Patients Whose Diagnosis of TNK Lymphoma Was Confirmed Histologically and By an Immuno-Histochemical Study. The Classification Adopted Was That of The World Health Organization (WHO) For Lymphoma (2008). The Treatment Was Based on Exclusive Radiotherapy for Four Patients Classified Stage IE, Radio-Chemotherapy for Five Patients: All Classified Stage IE Diffuse, And One Patient Classified Stage IV. Exclusive Chemotherapy Was Performed in Four Patients: Classified Stage IIE In Three Cases and Stage IE Diffuse in One Case. The Mean Follow-Up of Our Patients Was 8 Months (2-42 Months). Clinical Remission Was Noted Only in Two Patients.
8 Using the Pelvic Floor Impact Questionnaire and Lifestyle Modifications to Improve Symptoms of Pelvic Floor Dysfunction , Marc Bonis
Objective: The purpose of the study was to determine if lifestyle modifications along with a specialized exercise program improved symptoms and pain levels due to pelvic floor dysfunction.Subjects: 36 women aged 45.5 ± 9.1 years old (mean ± s.d.) identified with symptoms of pelvic floor dysfunction.Methods: The subjects were assessed for symptoms of pelvic floor dysfunction using the Pelvic Floor Impact Questionnaire (PFIQ–7). After a 30-day control period of no changes to lifestyle and activities, the subjects were introduced to lifestyle modifications and a specialized exercise program that included eight 45-minute live group sessions and a home exercise program to be performed at least three times per week. The subjects were re-assessed after completion of the intervention. IBM SPSS Version 24 statistical programming was used, and Wilcoxon non-parametric analyses were applied to compare the pre- and post-intervention data to determine if significant relief from dysfunction occurred. Results: The intervention significantly improved pelvic floor disorder symptoms (PFIQ-7, z (36) = -3.777, p < 0.05) and diastasis recti separation, (z (36) = -4.926, p < 0.05). The level of significance was set at p = 0.05.Conclusion: Lifestyle modifications and a specialized exercise program can significantly improve symptoms of pelvic floor dysfunction.
9 Evaluation of Antidiarrheal Activity of Aqueous Leaf Extract of Anogeissus leiocarpus on Castor Oil-Induced Diarrhea in Rats , Michel Archange Fokam Tagne1*, Yaouke Rékabi1, Paul Aimé Noubissi2, Gaëtan Olivier Fankem3, Hypolyte Akaou1, Henri Wambe4 and René Kamgang3,5
Diarrheal diseases are a major public health problem in developing countries. Anogeissus leiocarpus (DC.) Gill. & Perr (Combretaceae) is used in Africa and particularly in Cameroon for the empirical treatment of diarrhea. The present study was undertaken to evaluate the effects of aqueous extract of leaves of Anogeissus leiocarpus on castor oil-induced diarrhea in rats. Diarrhea was induced by administering 10 mL/kg body weight of castor oil orally to male rats. The determination of effective doses was made by assessing the weight and frequency of diarrheal stool of different doses of the extract (25 mg/kg, 50 mg/kg, 100 mg/kg, 200 mg/kg and 400 mg/kg). The effects of the aqueous extract of Anogeissus leiocarpus on intestinal transit were determined with an activated charcoal meal in rats. The effects of the aqueous extract of Anogeissus leiocarpus on intestinal secretion were evaluated by measuring the volume of the intestinal content and by dosing the electrolytes (Na+, K+ and Cl-) in the intestinal content by the colorimetric method. Castor oil-induced diarrhea was significantly inhibited (P <0.01) by 59.93%; 69.39%; 68.88%; 67.60% and 75.00%, respectively in the animals treated with the aqueous extract of the leaves of Anogeissus leiocarpus at doses of 25 mg/kg, 50 mg/kg, 100 mg/kg, 200 mg/kg and 400 mg/kg. The intestinal transit was inhibited significantly (P <0.01) by 29.34%, 31.35% and 43.29%, respectively of the aqueous extract of A. leiocarpus at doses 25 mg/kg, 50 mg/kg and 100 mg/kg. The volume of the intestinal content was decreased significantly (P <0.01) by 53.91%, 83.43% and 72.17%, respectively in the animals treated with the extract at doses 25 mg/kg, 50 mg/kg and 100 mg/kg as well as the concentration of electrolytes. These results would justify the use of leaves of Anogeissus leiocarpus in the treatment of diarrhea in traditional medicine.
10 Polymeric Nanoencapsulation of Indocyanine green for Photodynamic Therapy Technique , Mohammadreza Saboktakin
Indocyanine green (ICG) has been exploited as a photosensitizer for use in cancerous phototherapy including breast, brain, and skin tumors. Although ICG is of particular advantage for use in cancer phototherapy, it adversely tends to disintegrate in aqueous medium and such degradation can be markedly accelerated by light irradiation (photodegradation) and/or heating (thermal degradation). Furthermore, ICG after administered intravenously will be readily bound with blood proteins and hence leads to only 2±4min of plasmatic half-life. Among various pharmaceutical polymers, poly (lactic-co-glycolic acid) (PLGA), PEG, Chitosan are the best-defined biomaterials with FDA approval for drug encapsulation due to its biocompatibility, biodegradability, and controllability for drug release. This review shows that novel applications of biodegradable polymers as nanocarrier for ICG to improve of physicochemical properties of ICG such as Half-life.
11 Transpersonal Caring Relationship , Joyce Reder
The enduring values and beliefs that brought me to nursing include a desire to have purpose in my life. This means I want to know that I did not waste my time on earth. Another belief is that every person deserves to be cared for by compassionate caregivers. My compassion for others comes from my belief in all people being children of God. My religious values are the most important beliefs I hold. Faith gives people a reason for everything they do. I believe we will be judged by God at the end of our time on earth and I want to be worthy of redemption. Caring for those who are sick or can-not care for themselves is, in my opinion, helping to do God’s work. Hopefully this work will assist in my being judged favorably.
12 Epidemiology, Diagnosis & Prevention of Newcastle Disease in Poultry  , Mebrate Getabalew1, Tewodros Alemneh2*, Dawit Akeberegn3, Daniel Getahun1 and Derbie Zewdie1
Newcastle disease is a contagious bird disease affecting many domestic and wild avian species. It is a zoonotic disease with widespread distribution. It is caused by avian Paramyxovirus serotype 1 virus which, with viruses of the other eight serotypes (avian paramyxovirus1-9), has been placed in the genus Avulavirus, sub-family Paramyxovirinae, family Paramyxoviridae. Virulent ND virus strains are endemic in poultry in most of Asia, Africa, and some countries of North and South America. Other countries, including the United States of America and Canada, are free of those strains in poultry. The strain of Newcastle pathogenicity can be classified into five pathotype: Asymptomatic enteric strain; Lentogenic strain; Mesogenic strain; Viscerotropic velogenic strain and Neurotropic velogenic strain. Clinical signs are extremely variable depending on the strain of virus, species and age of bird, management, concurrent disease, and pre-existing immunity caused by Paramixovirus with worldwide distribution affecting chickens of all age groups. The transmission of ND occurs through respiratory aerosols, exposure to fecal and other excretions from infected birds, through newly introduced birds, selling and giving away sick birds and contacts with contaminated feed, water, equipment, cannibalism and clothing. Gasping, coughing, sneezing, rales, tremors, paralyzed wings and legs, twisted necks, circling; colonic spasms and complete paralysis are the clinical pictures of the disease. Newcastle disease may cause conjunctivitis in humans, when a person has been exposed to large quantities of the virus. The objective of this review is, therefore, to understand the epidemiology, clinical signs, diagnosis, prevent and control of Newcastle disease in poultry.
13 Air Pollution, Health and Ethics , Robin Attfield*
Recent findings about nitrogen dioxide pollution in Britain and about particulate pollution worldwide raise ethical issues about the protection of human (and animal) health [1]. Many urban areas of Britain have been found to have illegally high levels of NO2. But it turns out that there is a world-wide problem with particulates, particularly in large towns and cities in Third world countries, as well as in much of Europe and North America. In many cases diesel engines are to blame. Does it follow that these should be phased out as soon as possible? Many of us would answer ‘yes’. But before we do, we should reflect on the broader picture. The aims of this presentation are to begin this undertaking, adduce relevant ethical principles, and to draw conclusions which are not invariably the ones that we might well adopt prior to reflection. First, can we phase out diesel engines? With automobiles, this is certainly possible, and it is open to governments to introduce scrappage schemes, encouraging people to trade in their diesel-powered cars and replace them with petrol-powered ones. But even this, as we shall see, is not unproblematic.
14 Electron Microscopy Study of Nerve Cell Death Types in Some Central Nervous System Diseases. A Review , Orlando J Castejón*
In the present review we describe the nerve cell death types in some nervous central diseases. Cortical biopsies of patients with congenital hydrocephalus, brain trauma, vascular anomalies and brain tumors are examined by means of transmission electron microscopy to study distinct and combined forms of nerve cell death. Most non-pyramidal nerve cells, astrocyte and oligodendrocytes undergo a hybrid oncotic-apoptotic and necrotic continuum process. In a lesser proportion another non-pyramidal nerve cells, astrocytes and oligodendrocytes show apoptosis or oncosis only. Autophagic cell death was rarely seen in non-pyramidal nerve cells in traumatic brain edema. The nerve cell death is discussed in relation with the severity of brain edema, anoxic-ischemic conditions of the tissue, calcium depolarization and Ca ++ influx, resulting in excitotoxic cell death, glutamate excitotoxicity, caspase dependent and independent mechanisms, oxidative stress, and calcium overload.
15 The Developmental Tasks and The Binge Drinking , Lidia Susana Mendes Moutinho*
In the last decade alcohol consumption in Europe has stabilized, nevertheless a high rate of Binge Drinking (BD) still occurs which means a consumption over 60gr or more of pure alcohol in one occasion at least once in the last month. This type of consumption is the most appreciated by the young people. The age of BD is most prevalent between 20-24 years [1].The age range in which this type of consumption has more followers is also the age that the integration of many developmental tasks is expected. According to Theory of Development of Erickson the people between the ages of 20 and 35 are in the stage designated as young adults. This stage of development suggests significant changes and an increase of responsibility which is a long-term commitment to sharing, companionship, monogamous relationships and a desire to start a family.
16 The Developmental Tasks and The Binge Drinking , Lidia Susana Mendes Moutinho*
In the last decade alcohol consumption in Europe has stabilized, nevertheless a high rate of Binge Drinking (BD) still occurs which means a consumption over 60gr or more of pure alcohol in one occasion at least once in the last month. This type of consumption is the most appreciated by the young people. The age of BD is most prevalent between 20-24 years [1].The age range in which this type of consumption has more followers is also the age that the integration of many developmental tasks is expected. According to Theory of Development of Erickson the people between the ages of 20 and 35 are in the stage designated as young adults. This stage of development suggests significant changes and an increase of responsibility which is a long-term commitment to sharing, companionship, monogamous relationships and a desire to start a family.
17 Miraculous Healing and Long-Term Medical Remission of Systemic Lupus Erythematosus (SLE) – the role of Divinity within the Future of Medicine , Richard Sarnat* 
While “miraculous healings” or spontaneous medical remissions of various disease states have been scientifically reported previously, the exact mechanism, which allow for these seeming miracles or spontaneous remissions is poorly understood. By contrast, I have recently published multiple case studies of long term medical remissions, which have included the “miraculous healings” of Sarcoidosis, Chronic Lyme Disease, Fibromyalgia, Parkinson’s disease, severe chronic debilitating plantar arthritis and metastatic squamous cell carcinoma without the use of pharmaceuticals or antibiotics and where the mechanism of action used to initiate the “miraculous healing” appears to have a cause and effect relationship and thus is reproducible.This case report now adds Systemic Lupus Erythematosus (SLE) (case study #7) to the previous six case studies, which I have observed and now report to be successfully treated by a process, which Master John Douglas refers to as “Angelic Reformation.” These case reports are representative of the many hundreds of case studies I have documented (although most yet unpublished) over a ten-year period, while observing the work of Master John Douglas and the graduates of his Elite Development course. While certainly inspiring, admittedly all of these observations must ultimately be subjected to additional rigorous scientific methodology. Yet, the sheer number of miraculous healings I have observed and the fact that this body of knowledge can be taught to others who obtain similarly effective results is very promising, given our current confusion regarding the exact mechanisms of action and/or causation of autoimmune diseases, dementias and many other chronic disease states.
18 Antibiotic with Essential Metals Complexation and Interaction, An in Vitro Study by Spectrophotometric Method , Jinnat Begam Tumpa and Md Shahidul Islam*
The present research work describes of interaction and complexation studies of Amoxicillin with essential metal & antacid and also investigation of antimicrobial activity of Amoxicillin. Amoxicillin included the third generation drug of penicillin. In vitro analysis, Amoxicillin must be interacted with metal like Mg2+ and Mn2+. At pH 7.4, this study was performed in different ratios of Amoxicillin with metal and antacid both at room temperature 250 0C. by this study, it is investigated that drug Amoxicillin is complexed with metal as well as antacid which is confirmed by job’s plot. This experiment was carried out by using ultra violet spectrophotometer. The microbial sensitivity test is important to know whether there is any change in the effectivity of Amoxicillin after the interaction with metals. There was a remarkable change in the effectivity of Amoxicillin and its complexes. This research work confirms that there was interaction between Amoxicillin with Metals like Mg2+ and Mn2+ which was confirmed by Job’s plot method by spectrophotometric assay.
19 A Review Study on Different Plants in Malvaceae Family and Their Medicinal Uses , Upama Das and Md Shahidul Islam*
In this investigation, a total of 5 species under 5 genera belonging to the malvaceae family were mentioned. In this study Taxonomy and traditional medicine practices on Malvaceae family of Chittagong, Bangladesh was carried out. The plants which were used by local people, were surveyed and collected . The members of this family have mucilaginous substance. Stellate hairs are usually present on their young parts. Flower Bracteate/ebracteate, Bracteolateor Ebractiolate, Pedicellate, Dichlamydeou Spentamerous, complete, actinomorphic, regular, bisexual and hypogynous. Out of the total number of species Abutilon indicum (L.) Sweet., Hibiscus esculentus L., Hibiscus mutabilis L., Hibiscus rosa-sinensis L., were common and Gossypium herbaceum L. was rare species in the study area. Detailed survey has made in gathering information regarding use of medicine has been documented. Usually, the survey in each locality started with the interview of elderly and experienced members, locally known as Hakims. Besides, this the common people of the surveyed localities who themselves have used these plant based for health treatments were interviewed to prove veracity of the curative features of plants. Medicinal uses and data about the treatment of various alignments based on the information gathered by using questionnaires are given subsequently. For each species botanical name, local name, habit, habitat, phenology, status of occurrence, and medicinal uses have been mentioned.
20 Effectiveness of Nutrition Education on Nutrient intake and Nutrition Status of infants in Ondo State, Nigeria , Akinrinmade R1*, Njogu E2 and Ogada I3
Malnutrition during infancy has been linked to lack or low knowledge of appropriate feeding practices of the caregivers. This study determined the effectiveness of nutrition education on Minimum Acceptable Diet (MAD) as an indicator of complementary feeding to achieve the nutrient intake and nutrition status of infants (6-11months) in Ondo State, Nigeria. The study was a cluster randomized controlled trial design, whereby the participants were assigned to two groups. One intervention and one control group in a ratio of 1:1. The sample size was 142 for intervention group and 142 for the control group. Nutrition education on MAD was carried out among the caregivers in the intervention group and the control group received no nutrition education. The nutrition education was based on dietary diversity and meal frequency putting into consideration the hygiene practices. To determine the nutrient intake of the infants, data was collected from caregivers as the infants progressed in age using questionnaires. nutrient intake of the infants was assessed using 24-hr dietary recall. Data were analyzed using SPSS version 22.0. From the analysis, there was no significant difference in demographic and socio-economic status of the caregivers and Nutri-survey software for the nutrient intake. There was no significant difference in the complementary food intake of the infants as intended by the caregivers at the baseline. At the midline and the endline after the nutrition education, the nutrients intake of the infants in the intervention group was higher than the nutrient intake of the infants in the control group as analyzed using nutri-survey. Energy intake of infants in the intervention group was higher both at the midline (259kcal±20.67) and at the endline (366.7kcal±23.03) than those in the control group both at the midline (121.1kcal±17.05) and the endline (212kcal±22.04). There was a significant difference in WAZ (t. test; p=0.001), WAZ (t. test; p=0.001) but no significant difference in HAZ (t. test; p=0.049). There was an association between meal frequency and under nutrition (AOR: 0.489 (0.26-0.92) p-value; 0.027, dietary diversity and stunting (AOR:1.493 (1.25-1.80) p-value; 0.001).
21 Female are More Prone to Halitosis Due to the Changing of the Hormonal Balance-A Cross Sectional Study in Bangladesh , S M Mahmudul Hasan*, Sumia Afrin and Nafees Uddin Chowdhury
Introduction: Halitosis is the highly public health concern and about female are commonly affect this problem. A steroid sex hormone that acts as an important role in maintaining of oral physiology. The menstrual cycle pointed as a constituent that causes halitosis. The prevalence rate of halitosis during menstrual cycle unknown and various sociodemo graphic factors associated to the halitosis.Objective: The purpose of the survey was to get out the sociodemographic factors that cause halitosis during the menstrual phase.Methods: This study was cross-sectional survey, covering in Dhaka district of Bangladesh and data collecting period February 2017 to January 2018. The menstruation is 28 days between the days menstrual phase-1-4, follicular phase-7-11 and premenstrual phase-24-27 days. Anxiety score measured by using the Beck Anxiety Inventory (BAI) questionnaire. Factors of halitosis during menstrual cycle risk measured by cross-tabulation and ordinal logistic regression were used to examine the association between sociodemo graphic factors halitosis during menstrual cycle.Results: Results showed that about 75% of participant were suffering from severe halitosis. In the adjusted model, high-level anxiety versus low-level anxiety (AOR=0.05,95% CI=0.02,0.23) and medium level anxiety (AOR=0.09,95% CI=0.02,2.69); rural versus urban (AOR=3.41,95% CI=1.24,9.34) was significant for malodor during the menstrual phase.Conclusion: This work confirmed the demographic factors were exacerbated oral halitosis during the menstrual phase.
22 Female are More Prone to Halitosis Due to the Changing of the Hormonal Balance-A Cross Sectional Study in Bangladesh , S M Mahmudul Hasan*, Sumia Afrin and Nafees Uddin Chowdhury
Introduction: Halitosis is the highly public health concern and about female are commonly affect this problem. A steroid sex hormone that acts as an important role in maintaining of oral physiology. The menstrual cycle pointed as a constituent that causes halitosis. The prevalence rate of halitosis during menstrual cycle unknown and various sociodemo graphic factors associated to the halitosis.Objective: The purpose of the survey was to get out the sociodemographic factors that cause halitosis during the menstrual phase.Methods: This study was cross-sectional survey, covering in Dhaka district of Bangladesh and data collecting period February 2017 to January 2018. The menstruation is 28 days between the days menstrual phase-1-4, follicular phase-7-11 and premenstrual phase-24-27 days. Anxiety score measured by using the Beck Anxiety Inventory (BAI) questionnaire. Factors of halitosis during menstrual cycle risk measured by cross-tabulation and ordinal logistic regression were used to examine the association between sociodemo graphic factors halitosis during menstrual cycle.Results: Results showed that about 75% of participant were suffering from severe halitosis. In the adjusted model, high-level anxiety versus low-level anxiety (AOR=0.05,95% CI=0.02,0.23) and medium level anxiety (AOR=0.09,95% CI=0.02,2.69); rural versus urban (AOR=3.41,95% CI=1.24,9.34) was significant for malodor during the menstrual phase.Conclusion: This work confirmed the demographic factors were exacerbated oral halitosis during the menstrual phase.
23 Prediction of the State of the Cardiovascular System based on the Allocation of the Boundaries of the Implementation of the Dynamic System , NT Abdullayev*, OA Dishin, ID Ibragimova and KhR Ahmadova
Recently, research methods for rare experimental events have been intensively developed [1-9]. For a quantitative assessment of rare events, the time intervals between occurrences of successive events above (or below) some threshold Q are usually considered. In this case, both the probability density function of these repeated intervals and their long-term dependencies are investigated (autocorrelation function, conditional repetition periods, etc.). In the numerical analysis necessarily considers not very large thresholds Q, which provide good statistical estimates of repeated intervals, and then these results are extrapolated to very large thresholds, for which the statistics are very poor [1-5].
24 Is Cannabidiol the Cure-all Remedy we Have Been Looking for? , Leona Chang and Olga Ostrovsky*
Cannabidiol (CBD), the second major component of the plant Cannabis sativa, has become increasingly popular for its potential anxiolytic, anti-inflammatory, antiemetic, and antipsychotic effects. It is non-psychotropic and has no abusive potential thus far, however scientific evidence on the pharmacological effects of CBD are limited to preclinical studies. More large and well-controlled clinical trials are needed to establish the clinical applications of CBD.Cannabis sativa is one of three primary species from the Cannabaceae family, known for its cannabinoid extract, delta-9-tetrahydrocannabinol (∆9-THC,). ∆9-THC is the most abundant component of Cannabis sativa and is popular for its psychoactive or euphoric effects. On the contrary, the second major component of the plant Cannabis sativa-cannabidiol (CBD)-does not have psychoactive effects; it has received the latest media buzz and marketing claims as a miracle cure for anxiety, depression, pain, inflammation, insomnia, and even cancer, without the high.CBD can be derived from varieties of Cannabis, commonly referred to as hemp or marijuana. Hemp and marijuana differ by the amount of ∆9-THC in the plant. The Agriculture Improvement Act of 2018 (or 2018 Farm Bill) defines “hemp” as any part or derivative of the plant Cannabis sativa, with a ∆9-THC concentration of no more than 0.3% by dry weight, in contrast to up to 30% of ∆9-THC which is in marijuana [1]. The 100-fold difference in the psychoactive component of Cannabis sativa is likely the growing public’s interest in the potential therapeutic effects of CBD.Products advertised to contain CBD have been increasingly found in oils, creams, cosmetics, gummies, and even dog treats. The increasing availability of cannabis-derived products is due to the passage of the 2018 Farm Bill which legalized hemp cultivation and declassified it as a Schedule I controlled substance. Now hemp-derived CBD is widely available in almost all 50 states. With the overwhelming ease in purchasing CBD products, what is the scientific evidence on CBD as a cure all drug and is it safe to use? There are a variety of pharmacologic effects of CBD reported in preclinical studies such as anxiolytic, anti-inflammatory, antiemetic, and antipsychotic properties (Figure 1).