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Paper Details

Microwave assisted solid support synthesis of some3, 5-Diaryl- D2 -isoxazolines as potential antibacterial agents

Sheetal Shakhawat, Anju Devpura, Jayant P.Sing, Parul Sharma , Laxmi Lal Dangi and Shiv Sing Dulawat*

Journal Title:Journal of Chemical, Biological and physical sciences
Abstract


An environmentally benign microwave assisted one pot approach for the synthesis of some 3,5-diaryl-D2 -isoxazolines from substituted chalcones with hydroxylamine hydrochloride using basic alumina for its catalytic role as well as energy transfer medium is described. The reaction rate is brought down from hours to minutes along with improved yield as compared to conventional heating. All the synthesized compounds were tested for their in vitro antibacterial activity.

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