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Paper Details

Eco-friendly Synthetic Route for New Pyrazolines Bearing Sulfonamido and Quinolino Pharmacophore in PEG-400

Vasant B. Jagrut1, Dinesh L. Lingampalle2, Rajendra P. Phase3, Wamanrao N. Jadhav3*

Journal Title:Journal of Chemical, Biological and physical sciences

A series of new 3-(4'-tosylaminophenyl)-5-(2'-chloro-substitutedquinolin-3-yl)-4,5-dihydro pyrazolines (2) have been prepared by carrying cyclocondensation of 3-(2-chloro-substitutedquinolin-3-yl)-1-(4- (tosylamino)phenyl)prop-2-en-1-ones (1) with hydrazine using grnner reaction media, polyethylene glycol (PEG-400) at room temperature.