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Paper Details

Busulfan-induced lipid peroxidation: Protective role of morin

Supratim Ray

Journal Title:Journal of Chemical, Biological and physical sciences
Abstract


Considering drug-induced lipid peroxidation as a possible mediator of drug-induced toxicity and exploiting the free radical scavenging action of antioxidants, the present study was designed to evaluate the antiperoxidative potential of morin on busulfan-induced lipid peroxidation. The study was performed in vitro using goat liver as lipid source. This evaluation was done by measuring the 4-hydroxy-2-nonenal (4- HNE) and nitric oxide (NO) content of liver tissue homogenates as markers of lipid peroxidation. The study reveals the lipid peroxidation induction capacity of busulfan and the antiperoxidative potential of morin on busulfan-induced lipid peroxidation

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