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Paper Details

Synthesis and characterization studies of a bivalent metal chelate

Suman Malik1 and Jaishree Morey2*

Journal Title:Journal of Chemical, Biological and physical sciences

The synthesis of a hetero-chelate of the type ML2.2H2O has been reported here. The metal complex of Co(II) Complex has been synthesized with 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2- yl)methylsulfinyl]-1H-benzo[d]imidazole(Pantoprazole). Pantoprazole is a proton pump inhibitor (PPI) drug that inhibits gastric acid secretion. Proton pump inhibitors (or PPI) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. Conductometric titrations have suggested metal-ligand ratio of 1:2 for Co(II) complex. The ligand behaves as a bidentate with N, O donor atoms. Complexes have been synthesized and characterized by elemental analysis, UV-visible and IR spectral studies.