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Paper Details

In-vitro Antimalarial Evaluation of Novel Functionalized Chalcones

Kunwarvir Singh1, Amit Sahu2, Manisha3* and Lal Singh1

Journal Title:Journal of Chemical, Biological and physical sciences
Abstract


Novel chalcones have been synthesized by conventional method. They were evaluated for their invitro antimalarial activity against chloroquine sensitive strain of Plasmodium falciparum (NF-54). Of the 14 compounds synthesized, 3 compounds viz, 6f, 6g and 7g were found to be most potent and shown IC50 values in the range 2-9 ?g/mL.

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