Negative ion mode mass spectrometry- an overview
Pavani Challamalla, Somsubhra Ghosh*, N. Parthiban, K. N. V Rao and David Banji.
Journal Title:Journal of Chemical, Biological and physical sciences
Negative ion mode Mass spectrometry is the most comprehensive and versatile tool. Recent advances
in negative ion mode mass spectrometry have improved sensitivity, identification and elucidation of
organic and inorganic compounds. All compounds will not produce negative ions but many important
compounds of environmental or biological interest can produce negative ions under the right
conditions. For such compounds, negative ion mode mass spectrometry is more efficient, sensitive and
selective than positive ion mass spectra. In this review, discuss the overall framework of the negative
ion mode mass experiments into its key components, such as principle, ionization techniques,
instrumentation, fragmentation and applications.