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Paper Details

A Facile Route to the Synthesis of 8-[2-(3, 5- Dimethyl-4-Ethoxy Carbonyl Pyrrolyl) Hydrazine] Substituted Phenothiazines and their Biological Activity

M. N. Narule

Journal Title:Journal of Chemical, Biological and physical sciences

A short facile synthesis of 8-[2-(3, 5-dimethyl-4-ethoxy carbonyl pyrrolyl) hydrazine] substituted phenothiazines (5a-j) from 2-arylamin benzal-2-(3?,5?-dimethyl-4?-ethoxy carbonyl pyrrole)hydrazines(4) in presence of sulphur and iodine.These compounds were screened for their antibacterial activity against S. aureus and E. coli as well as for their antifungal activity against C. albicans and A. niger. The synthesized compounds are characterized by FTIR, 1H NMR, elemental and chemical properties