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Paper Details

Synthesis and Fluorescence study of Novel4-{4-[(2 Z)-2- (2-hydroxybenzyli dene) hydrazine] benzyl}- 1, 3 oxazolid in-2-one

B. R. Thorata, Sudhir Sawant, Mustapha Mandewalea, Ramesh S. Yamgar and Ramdas G. Atramb

Journal Title:Journal of Chemical, Biological and physical sciences

The pharmaceutical important 4-(4-hydrazinylbenzyl)-1,3-oxazolidin-2-one hydrochloride (1) is condensed with salicylaldehyde (2) in methanol in presence of sodium methoxide forming schiff base 4-{4-[(2Z)-2-(2-hydroxybenzylidene)hydrazinyl]benzyl}-1,3-oxazolidin-2-one (3). It is characterized by TLC, FT-IR, and NMR spectroscopy. The IR peak at 1781, 3318 and 3230 cm-1 is due to O-CO-NH, -CO-NH- and =N-NH- stretching vibrations. The new peak at 1616 cm-1 is due to C=N- (imino) group. The compound (3) is further subjected to fluorescence study. The Schiff base (3) shows excitation at 276 nm (? 9.203) and 400 nm (? 3.129) and mission at 413 nm (? 580) for excitation at 276 nm & 403 nm (? 234.58) and 403 nm (? 432.70) for the excitation at 400 nm.