Determination of DPPH free radical scavenging oxidation effects of methanolic leaf extracts of some Indian medicinal plant species.
Ashokkumar R* and M. Ramaswamy
Journal Title:Journal of Chemical, Biological and physical sciences
The objective is to determine the hydrogen donating radical scavenging
potential of methanolic leaf extracts of 4 selected medicinal plants such as
Phyllanthus amarus, Phyllanthus maderaspatensis (Family: Euphorbiaceae),
Senna auriculata (Family: Caesalpiniaceae) Solanum torvum (Family:
Solanaceae). The antioxidant potential of the extract was evaluated by 1,1-diphenyl-
1-picrylhydrazyl (DPPH) assay method. The concentrations of 15?l to75?l of methanol
leaf extracts of Phyllanthus amarus, Senna auriculata, Phyllanthus maderaspatensis
and Solanum torvum showed strong inhibitory activity ranges (against DPPH) such as
26%-73%, 18%-55%, 23%-71% and 23%-51% respectively which indicated strong
free radical scavenging (hydrogen donating) potential of the methanol extracts. Based
on the observed the IC50 values, it was concluded that the P.amarus showed highest
scavenging potential (0.045?g/ml) followed by P. maderaspatensis (0.05?g/ml),
S.auriculata (0.067?g/ml) and lowest potential by S.torvum (0.073?g/ml).