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Paper Details

Determination of DPPH free radical scavenging oxidation effects of methanolic leaf extracts of some Indian medicinal plant species.

Ashokkumar R* and M. Ramaswamy

Journal Title:Journal of Chemical, Biological and physical sciences

The objective is to determine the hydrogen donating radical scavenging potential of methanolic leaf extracts of 4 selected medicinal plants such as Phyllanthus amarus, Phyllanthus maderaspatensis (Family: Euphorbiaceae), Senna auriculata (Family: Caesalpiniaceae) Solanum torvum (Family: Solanaceae). The antioxidant potential of the extract was evaluated by 1,1-diphenyl- 1-picrylhydrazyl (DPPH) assay method. The concentrations of 15?l to75?l of methanol leaf extracts of Phyllanthus amarus, Senna auriculata, Phyllanthus maderaspatensis and Solanum torvum showed strong inhibitory activity ranges (against DPPH) such as 26%-73%, 18%-55%, 23%-71% and 23%-51% respectively which indicated strong free radical scavenging (hydrogen donating) potential of the methanol extracts. Based on the observed the IC50 values, it was concluded that the P.amarus showed highest scavenging potential (0.045?g/ml) followed by P. maderaspatensis (0.05?g/ml), S.auriculata (0.067?g/ml) and lowest potential by S.torvum (0.073?g/ml).