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Paper Details

Chemistry of Novel Biphnyltetrazolo-Triazole Derivatives- Their Synthesis and Microbial Evaluation

Vijay V. Dabholkar*, Navnath B. Shinde, Abhishek Karekar & Prem Naik

Journal Title:Journal of Chemical, Biological and physical sciences

N-(triphenylmethyl)-5-(4'-bromoethylbiphenyl-2-yl)tetrazole reacted with ethyl piprazin -1-carboxylet to obtained (1), which on further treatment with chlorosulphonic acid to Triphenyl group & yield (2) ,this compound then treated with hydrazine hydrate to give hydrazine derivative (3) which was then treated with active methyl group , corbondisulphite, ethylchloroformet, aromatic cyno compound to yielded the respective pyrazole ,Oxadiazole,indazole&triazole. The structures of the synthesized compounds confirmed by Physico-chemical test and spectral techniques, representative samples screened for their antimicrobial activity against gram positive and gram-negative bacteria.