Study of the Cytotoxicity Effect of New Cr (III), Co (II), Fe (III), and Cu (II) Complexes of Chalcone on Cancer (Cell Line Hep-2) and Antimicrobial Activity

Omar H. Al-Obaidi

Journal Title:Journal of Chemical, Biological and physical sciences
Abstract

A new series of Cr(III) , Co(II), Fe(III) and Cu(II) complexes with the chalcone ligand were studied on the growth of Hep-2 (Human hepatocellular ademocarcinoma ),which is the human larynx cancer cell Line by using in vitro system and compared with anticancer drug cisplatin (cis-pt) as appositive control. The cancer cells were treated with different concentration and cis-pt after 72 hr. exposure time. The cytotoxic activity was tested by inhibition rate as parameter. The results showed significant differences (p

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