Medicinal potential of Commiphora sponthulata, Hugonia casteneifolia and Raphidiocystis chrysocoma indigenous to Tanzania
Sylvester Leonard Lyantagaye
Journal Title:Journal of Chemical, Biological and physical sciences
Herbal medicines constitute a potentially important resource for new and safe
drugs for the management of microbial infections and other diseases. This study aimed at
examining whether or not crude plant extracts of Hugonia casteneifolia, Commiphora
sponthulata and Raphidiocystis chrysocoma have antimicrobial activities on some
pathogenic bacterial isolated from sick domesticated animals. Agar diffusion technique was
used to determine the inhibition of microbial growth and broth dilution technique was used
to determine MIC and MBC. The study has shown that R. chrysocoma extract is very potent
against Streptococcus agalactiae, Staphylococcus aureus and Escherichia coli, H.
casteneifolia is potent against S. agalactiae and S. aureus, and C. sponthulata extract is
potent against Salmonella gallinarum only. All the three plant extracts are non-cytotoxic.
This is the first scientific evaluation of the veterinary medicinal potential of the H
casteneifolia, C. sponthulata and R. chrysocoma from Tanzania, providing the baseline for
further investigations towards discovering new drugs.