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Paper Details

Withania somnifera: A Wild Plant Effective in Treatment of Various Types of Cancer

Monika Kumari

Journal Title:Journal of Chemical, Biological and physical sciences

Withania somnifera L. Dunal (WS), an Indian plant commonly known as ashwagandha has been used in Ayurvedic medicine for the treatment of arthritis, tumors, tuberculosis, chronic liver diseases and for immune-modulatory effects. Main plant part of WS with pharmacological importance is basically rooted. Biological active compounds especially steroidal lactones (withanolides, withaferins), are thought to be responsible for much of its pharmacological activities. These are found effective against many types of cancer specially the most common cancers such as breast cancer, prostate cancer. The effects of WS extracts have been demonstrated in vitro on human cancer cell lines, and in vivo on mice, but still there have been no human trials and it is not brought in market to cure cancer patients. This article focuses on researches done using WS extracts and its bioactive compounds on most common types of cancer.