Synthesis of Closantel as Effective Reaction Media for Hydrotropes
Jagannath J. Kadam1, K.George A2, R.S.Dhamnaskar3 and Manohar V Lokhande
Journal Title:Journal of Chemical, Biological and physical sciences
The paper describes the synthesis of Closantel. . It is used as an anthelmintic
i.e. an agent that destroys or causes the expulsion of parasitic intestinal worms so it is
used as Anti-worm drug. The synthesis of Closantel was carried out using four different
hydrotropes. The effect of various hydrotropes on yield, rate constant and activation
energy at various temperatures and concentrations are studied.