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Paper Details

Inflammatory Myofibroblastic Tumor in a Known Case of Squamous Cell Carcinoma of Same Site - A Rare Case Report with Review of Literature

Inflammatory Myofibroblastic Tumor in a Known Case of Squamous Cell Carcinoma of Same Site - A Rare Case Report with Review of Literature

Srinitya Mulukutla, Shubhra Sharma, Sachin Wani, Hiral Shah and Ankit Shah

Journal Title:Acta Scientific Otolaryngology
Abstract


Background: Inflammatory myofibroblastic tumor is a rare and distinct disease entity comprising of myofibroblastic cells with in-flammatory infiltrate. It was first described in the lungs in 1939 and since then few reports have been made of its occurrence in the oral cavity. As it clinically and radiologically mimics a malignant lesion, the correct diagnosis is imperative to avoid radical treatment.Methods: We describe a case of 44 year male with a significant past history of squamous cell carcinoma of buccal mucosa, presenting with Inflammatory myofibroblastic tumor arising from same site. Patient presented with a solitary, well circumscribed lesion arising from buccal mucosa and gingival sulcus. Results: Final histopathology was suggestive of inflammatory myofibroblastic tumor showing compact proliferation of spindle cells arranged in a storiform pattern, with predominantly lymphoplasmacytic cells infiltration.Conclusion: Inflammatory myofibroblastic tumor can be accurately diagnosed with thorough understanding of histology and im-mune profiling which avoids unnecessary and extensive treatment protocols. No other case with a previous history of Squamous cell carcinoma of same site has been reported in literature.Keywords:Buccal Mucosa; Inflammatory Myofibroblastic Tumor; Oral Squamous Cell Carcinoma