• We are available for your help 24/7
  • Email: info@isindexing.com, submission@isindexing.com


Paper Details

Impact of Blood Culture Utilization on Antibiotics Choice in Chemotherapy Induced Febrile Neutropenia in Solid Tumours

Impact of Blood Culture Utilization on Antibiotics Choice in Chemotherapy Induced Febrile Neutropenia in Solid Tumours

S Gilani, G Hegarty, J Whithurst and Z Rehman

Journal Title:Acta Scientific Cancer Biology
Abstract


Blood cultures are important tools for the evaluation of sepsis in febrile neutropenia (FN) patients. Febrile neutropenia remains a serious complication of anticancer systemic chemotherapy with increased mortality worldwide. NICE (National Institute of Clini-cal Excellence) UK issued clinical practice guideline to prevent and manage febrile neutropenia in cancer patients [1]. There was also a genuine concern about diagnostic dilemma and management of febrile neutropenia during recent pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) associated disease COVID-19 [2]. Healthcare resources were already limited and were overwhelmed rapidly by large influx of patients [3]. Routine medical care including management of cancer patient was severely disrupted [4]. This led to the developments of rapid guidelines to manage cancer patients across the world [5]. NICE and other bod-ies issued rapid guidelines to manage febrile neutropenia during COVID-19 period [6]. Majority of guidelines consider blood culture an essential part in assessment of sepsis in febrile neutropenia [1]. This prospective study was done in hospitalized patients who developed febrile neutropenia while on chemotherapy, looking at various factors and their impact on outcome. The objective of this study was to evaluate whether antibiotic choice is affected by blood culture utilization in febrile neutropenia [7].