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Assessment of Renal Function Tests and Serum Total Protein among Pregnant Women with Pregnancy-Induced Hypertension Attending in Asrade Zewudie Memorable Hospital (ASZMPH), Gojjam, Ethiopia: Case-Control Study

Assessment of Renal Function Tests and Serum Total Protein among Pregnant Women with Pregnancy-Induced Hypertension Attending in Asrade Zewudie Memorable Hospital (ASZMPH), Gojjam, Ethiopia: Case-Control Study

Haymanot Tewabe1*, Mistire Wolde1

Journal Title: Journal of Clinical Medical Research
Abstract


Background: Pregnancy-induced hypertension has remained a significant global public health threat in both developed and developing countries. Therefore, this study aimed to assess renal function tests and serum total protein among pregnant women with pregnancy-induced hypertension. Methods: A case-control study was done on 200 pregnant women, 100 with pregnancy-induced hypertension (case group) and 100 normotensives (control group) at Asrade Zewudie Memorable Primary hospital Gojjam, Ethiopia, from January 24, 2020 to April 30, 2020. 5 ml of venous blood was collected on the SST test tube and analysed for serum lipid profile, renal function test, and serum total protein. The analysis was done by using SPPS software (version 20.0). The level significance was set at a 95% confidence interval (p-value is less than 0.05 was considered clinically significant). Results: There was a significant increase in blood urea, and serum creatinine (p < 0.05) in case groups as compared to normal groups (p < 0.05). The elevation of serum total protein was not significant (p > 0.05). The outcome of the final multiple logistic regression model indicated that factors like Body Mass Index (BMI), habits of doing scheduled exercise, habit of drinking alcohol, habit of fruit consumption, trimester and gravidity were having significant association with high blood urea, and serum creatinine results of the study participants. Conclusion: It might be better for clinicians to use renal function tests as screening test than requesting other costly tests. Further studies in different areas of the country by considering life style variation also recommended.