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Ashy Dermatosis and Lichen Planus Pigmentosus: A Clinico Pathological Study in Republic of Yemen

Ashy Dermatosis and Lichen Planus Pigmentosus: A Clinico Pathological Study in Republic of Yemen

Mohammed Abdul Qader Almalmi1*

Journal Title: Journal of Clinical Medical Research

Background: Ashy Dermatosis (AD), or Ashy Dermatosis of Ramirez, F. Kerdel-Vegas and Erythema Dyschromicum Perstans (EDP) is a characterized by unknown origin which was reported first in EL-Salvador in 1957, later in Venezuela in 1961 (Latin America) and in the USA in 1966. In Japan it was diagnosed as Lichen Planus Pigmentosus in1956. Objective: The objectives of the study are: To assess the clinical and histopathological characteristics of patients with ashy dermatosis and Lichen Planus Pigmentosus and define their differences or similarities of a study populations of 33 To find out the relation of socioeconomic status in Yemeni patients with Ashy Dermatosis and Lichen Planus Pigmentosus To compare the prevalence of Ashy Dermatosis and Lichen Planus Pigmentosus in the Republic of Yemen with the other studies carried out in Latin America, North America, Europe, Japan and India Patients and Methods: Thirty three Yemeni Patients, 11 females and 22 males, 6-70 years old presented with itchy and non-itchy gray-blue dark brown hypo-and hyperpigmented maculo-papular. Skin eruptions in the face,neck, trunk and upper and lower limbs, of several months duration were studied. Comprehensive blood images, seroiogical tests for syphilis, skin scraping for fungi, Wood’s light and rheumatoid factor, stool and urine analyses showed no abnormalities. A skin biopsy with subsequent histopathological examination was done in all selected patients. Results: The clinical data, investigations and the histopathological findings showed that 23 patients (5 females and 18 males) suffered from Ashy Dermatosis (AD) and 10 (6 females and 4 males) of Lichen Planus Pigmentosus. Conclusion: 33 patients out of 26.324 dermatology out patients seen during (96-98) presented with Ashy dermatosis or Erythema Dyschromicum Perstans (0.087%) and Lichen Planus Pigmentosus (0.037%) were very rare in Al-Kuwait University Hospital Sana’ a City, Republic of Yemen. These two diseases are different clinically but similar histopathologically. This study did not elicit exact etiological factors but racial, nutritional and environmental factors are suspected. Most of those patients were poor and working as farmers and street vendors and by during so were exposed to sunlight.