Treatment of Intrabony Defects by Decortication with CeraboneTM and DFDBA - A Randomised Controlled Trial
Irfana S Babrawala1, Rudrakshi C2*, Prabhuji MLV3, Shobith S Mampuzha4, Divya Khanna1, Deepthi Dharmaraj Sali1
Journal Title: Journal of Dental Health and Oral Research
Objective: Decalcified Freeze Dried Bone Allograft (DFDBA) and xenografts have shown good results in the management of intrabony defects. Decortication of the bone has shown favourable results in guided bone regeneration procedures. The goal of the present study was to check the efficacy of decortication with decalcified freeze dried bone allograft (DFDBA) and Cerabone™ bone grafts and to compare the response between the bone grafts placed using Radiovisiography (RVG) and Cone Beam Computed Tomography (CBCT) in intrabony defects.
Methodology: In this split mouth study, ten patients presenting with bilaterally intrabony defects were selected and decortication was done in all the defects. They were randomly allocated as Group I which received DFDBA and Group II received Cerabone™. Clinical parameters included Pocket Probing Depth (PPD), Relative Attachment Level (RAL), Plaque Index (I), Periodontal Disease Index (PDI) and Gingival Bleeding Index (GBI). Radiographically Intrabony Defect Depth (IBD) and defect resolution were measured at baseline, 3 months, 6 months and 9 months with RVG. CBCT was used at baseline and 9 months.
Results: Both the groups demonstrated statistically significant PPD reduction, attachment gain and radiographic bone fill. The differences between the groups were statistically significant and more favourable in Group II.
Conclusion: Decortication plus Cerabone™ significantly improved the clinical and radiographic parameters of intrabony defects at 9 months after treatment when compared to decortication plus DFDBA.