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Paper Details

Acral Cutaneous Manifestations during COVID-19 Outbreak  

Acral Cutaneous Manifestations during COVID-19 Outbreak  

Ramon Grimalt1*, Mario Cutrone2

Journal Title:Journal of Dermatology Research

We describe a patient with multiple cutaneous lesions resembling chilblains affecting her feet. She was one of 5 patients with these findings that we have seen during the last week, 4 of them in Venice, Italy, one of them in Barcelona, Spain. A 15-year-old girl with no relevant clinical history presented with reddish asymptomatic spots on her feet. No one in her family nor social environment has been diagnosed by COVID-19 since confinement. On examination, we observed the presence of chilblain-like vasculitical aspects such as microtrombotic-like reddish and purpuric macules (Fig. 1). The girl had no symptoms associated with upper respiratory tract infections, nor myalgia, fever nor headache. We performed fast serology PCR testing on the patient, which provided negative results. Four other patients with similar skin findings (and no other symptoms) were seen at the Pediatric Dermatology unit in Venice, Italy. PCR swab tests in these patients were negative for COVID-19 in all cases In the past week, we have seen 5 patients affected by a new dermatological manifestation, all coinciding with the outbreak of COVID-19 infection throughout the world. They were all asymptomatic adolescents from 12 to 16 years of age. But none of them had a positive family history for COVID-19 infection. In most cases the cutaneous vasculitical like eruptions appear in very mild or totally asymptomatic forms of the disease and mostly in adolescents. It seems to appear at the end of the process. They appear on both hands and feet but predominately on feet. The tendency is for spontaneous resolution but we need more time to follow this up. It is rather surprising that the PCR in all these patients was negative but, as onset occurred at the same time as the outbreak of COVID-19 it appears to suggest a clear relationships between the two. Recently one patient with similar clinical findings was biopsied in Switzerland (personal communication) by Prof Daniel Hohl and showed a lividoid occlusive vasculopathy. Other dermatological findings of COVID-19 infection include signs of small blood vessel occlusion. Also petechiae or tiny bruises, transient lividoid eruptions, acrocyanosis and pseudo chilblain lupus have been reported [1-4].