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Paper Details

Looking for New Strategies for Gynecological Cancer

Looking for New Strategies for Gynecological Cancer

Margarita S Alfie1 and Adrian P Hunis2*

Journal Title:Acta Scientific Cancer Biology
Abstract


In order to achieve better results in survival, new strategies try to cover that need not meet in gynecological cancers. At the ASCO Annual Meeting several works for ovarian cancer will be presented. The Surgical treatment without residual disease is associated with better survival and prognosis. Additional strategies to achieve complete response were evaluated in the abstracts session. Folate receptor α is overexpressed in a number of solid tu- mours, such as ovarian. Pafolacianine sodium is a fluorescent marker made of near- infrared dye and a ligand that allows it to bind to receptors over- expressed in ovarian cancer cells. When injected, the agent binds to folate receptors and will illuminate when used under near- infrared light. This mechanism of action allows for greater confi- dence that surgery resulted in a complete resection. Pafolacianine sodium injection is injected as a single-dose intravenous infusion prior to surgery.