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Paper Details

A Review on Systemic and New Cancer Hallmarks

A Review on Systemic and New Cancer Hallmarks

Akruti Amol Ingole1, Anjali Vijay Petle2, Surbhi Balwant Dhoke3, Piyush Jagdish Balgote4, Anirban Goutam Mukherjee5 and Uddesh Ramesh Wanjari3*

Journal Title:Acta Scientific Cancer Biology

The body system is dependent on each other through communication, cancer development can be supported by the new cancer- induced pathological systemic networks (CISPN), and the entire organism is “cancerized.” The significant anomaly in the transition of epithelial cells to mesenchymal cells plays a vital role in neural crest migration. The metastatic program follows a transformed cellu- lar communication process that, activated once, causes dispersed tumors at a distance from the original site. This review aims to pro- vide an idea of various systemic and new hallmarks and several altered networking processes that eventually end up causing cancer. Keywords: Cancer; Hallmarks; Inflammation; Cytokines; Tumor