Human Saliva: A Prognostic, Diagnostic and Therapeutic Tool-Kit
Journal Title:Acta Scientific Cancer Biology
Saliva is an extracellular fluid produced and secreted by salivary
glands in the mouth. About 93% by volume is secreted by the ma-
jor salivary glands and the remaining 7% by the minor glands. In
humans, biochemically, approximately 99% of saliva is water and
the other 1% is composed of organic and inorganic molecules .
Organic substances include exfoliated epithelial cells (from which
DNA can be extracted), white blood cells, mucus,, enzymes (such
as amylase and lipase), antimicrobial agents such as secretory IgA,
and lysozymes . Saliva consists of both full-length and partially
degraded forms of mRNA, its association with macromolecules
may protect salivary RNA from degradation .