Characterizing the Effects of Site-Specific Metastases on Nasopharyngeal Squamous Cell Carcinoma Survival
Christopher C Tseng, Jeff Gao, Gregory L Barinsky, Jordon G Grube, Christina H Fang, Jean Anderson Eloy and Wayne D Hsueh
Journal Title:Acta Scientific Otolaryngology
Introduction: To investigate the impact of site-specific metastases on survival and identify predictors of metastasis in patients with nasopharyngeal squamous cell carcinoma (SCC).
Materials and Methods: The National Cancer Database was queried for all cases of nasopharyngeal SCC between 2010-2016 which had metastasized to distant sites (460 cases). This was then further classified as metastases to bone, liver, lung, brain, and multiple sites. Univariate and multivariate analyses were used to compare patient demographics between sites. Kaplan-Meier analysis was applied to compare overall survival.