• We are available for your help 24/7
  • Email: info@isindexing.com, submission@isindexing.com


Paper Details

LA BIOLOGA MOLECULAR DE LEISHMANIA SPP. COMO PUNTO DE PARTIDA PARA NUEVAS ALTERNATIVAS DE TRATAMIENTO

Martha Cecilia Beltrn Cifuentes, Patricia Durn Ospina, Luisa Fernanda Corredor Arias

Journal Title:Investigaciones ANDINA
Abstract


Introduction: In Colombia there are research groups in Leishmaniasis that have joined forces to achieve the identification of the genome of Leishmania spp. As health professionals know this is a priority to understand the mechanisms of drug resistance. Methods: The databases used for this search were among others: NCBI PubMed MEDLINE, Science Direct, Nucleic Acids Research and Biochemical and Molecular Parasitology, as a publication of the journal Biomedical and several universities. Results: There are many species and vectors distributed throughout the country. The multiresistents created by Leishmania spp. rely especially in membrane proteins and mutations in the DNA of the parasite and their delivery systems. Conclusions: The PCR techniques should be implemented at the clinic to study resistance to drugs. The current protocols against Leishmaniasis not include additional alternatives. The treatments with immunomodulators are the new hope for treating this re-emerging disease.

Download