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ISSN(p): | ISSN(e):2582-211X

Paper Details

Antimicrobial Activity of Methanolic Extract of Flowers of Tridax Procumbens

D.S. Mohale, A.R. Pokrna, C.V. Sanghani, S.R. Rasekar, A.S. Rathi, A.S. Rathod, G.R. Mehetre, A.V. C

Journal Title:Indian Journal of Pharmacy and Pharmacology

Herbs are natural remedies for the disease with higher safety profile and efficacy . India is gifted with varieties of large number of medicinal herbs because of variety of climatic conditions and seasons favorable for growth of many species of plants. Amongst the large number of herbal drugs existing in India, very few have been studied systematically so far. Tridax procumbens (L) is a highly valuable drug and is one of the essential ingredients in the most of the compound preparations included in Ayurvedic literature. It is well known for number of pharmacological activities like hepatoprotective activity, anti-inflammatory, wound healing, Antidibetic activity, hypotensive effect, immunomodulating property, bronchial catarrh, dysentery, diarrhea and to prevent falling of hair, promotes the growth of hair, and antimicrobial activity against both gram-positive and gram-negative bacteria. The leaf juice shows antiseptic, insecticidal and parasiticidal properties, against conjunctivitis and is used also to check hemorrhage from cuts, bruises and wounds insect repellent. It is also used as bioadsorbent for chromium. Here we try to make attempt for focusing on antimicrobial activity of Tridax procumbens flowers. Their antibacterial activities were evaluated in vitro against clinical bacterial isolates. In effort to identify novel bacterial agents, this study was initiated to evaluate the antimicrobial properties of Tridax procumbens flowers extract against E. coli and Staphylococcus aureus by using disc-diffusion assay. The flower plant extracts demonstrated good antimicrobial activity against these bacteria tested with inhibition zones. The minimal inhibitory concentration (MIC) values of extract against the tested bacteria were found to 67.3 mg/ml and 48.20 against E.coli and Staphylococcus aureus respectively. The methanolic extract of flowers exhibited a pronounced activity against E. coli and Staphylococcus aureus. The minimum inhibitory concentration was found in methanolic Extracts of Tridax procumbens against test organisms.