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We should not underestimate Vitamin B12 and folic acid deficiencies in oldest old

Sema Akinci, Kamile Silay, Tuba Hacibekiroglu, Arife Ulas, Abdulkadir Basturk, Sule Mine Bakanay, Tekin Guney, Muhammed Bulent Akinci, Imdat Dilek

Journal Title:Basic Research Journal of Medicine and Clinical Science

Aim: It was aimed to investigate hemogram parameters, ferritin, vitamin B12 and folic acid levels of patients above age 80 who applied to the internal medicine outpatient clinic. Methods: Leukocyte, hemoglobin, platelet, ferritin, vitB12 and folic acid levels of total 200 patients (108 (54%) female and 92 (46%) male) age 80 and older were investigated retrospectively. Results: Out of 200 patients, 54 (27%) patients had normal hemogram. Hemoglobin levels of 58 (29%) cases were found normal, 138 (69%) were found low and 4 (2%) were found high. Leukocyte levels were normal in 144 (72%), leukopenia was detected in 28 (14%), and leukocytosis in 28 (14%) cases. Platelet levels of 129 (64.5%) cases were normal, 52 (26%) were assessed as thrombocytopenia and 19 (9.5%) as thrombocytosis. The deficiency anemia detected in 81 (58.7%) cases and the number of patients who has ferritin, vitB12 and folic acid deficiencies were 16 (19.7%), 27 (33.3%), and 19 (23.5%) respectively. Pancytopenia was detected in 18 (9%) patients and bicytopenia was detected in 30 (15%). Conclusion: The frequency of anemia is increased in the geriatrics population above age 80, deficiency anemia in particular. The present study is different from the literature since the most common deficiency was vitB12, following folic acid and iron deficiency. The importance of supportive treatment with vitB12 and folic acid replacement should not be underestimated in this population. Keywords: elderly, blood count, ferritin, vitB12, folic acid deficiency