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Paper Details

Risk factors for neonatal sepsis in paediatric ward at Khartoum North Teaching Hospital, Sudan

Mohamed Awadelkrim Ahmed, Omer Saeed Magzoub

Journal Title:Basic Research Journal of Medicine and Clinical Science

Infections are a frequent and important cause of neonatal morbidity and mortality. It was found that neonatal deaths account for a third of global child mortality and those infections are a major cause of neonatal mortality. Objectives: The aim of this study is to determine the common risk factors associated with neonatal sepsis and its relation to site and mode of delivery, birth weight, gestational age, onset of sepsis and the causative organisms in paediatric ward at Khartoum North Teaching Hospital. Methods: A cross-sectional prospective hospital based study was conducted on 120 neonates presented with neonatal sepsis who had been admitted to Khartoum North Teaching Hospital general pediatrics ward from January 2013 to of July 2013. History and physical examination were carried out, samples of blood were taken for blood culture and full blood count. Data was analyzed using the Statistical Package for Social Sciences (SPSS). Results: One hundred twenty neonates were studied. Sepsis was confirmed by clinical and laboratory measures. Sixty-seven (55.8%) neonates were males and 53(44.2%) were females. Fourteen (11.7%) were preterm, 99 (82.5%) were full term and 7(5.80%) were post dated. Early onset sepsis was detected in 79 (65.8%) neonates while late onset sepsis was detected in 41 (34.2%) neonate. The common risk factors were being delivered in the hospital 88(73.3%), history of fever or infection during pregnancy in 53(44.2%), low birth weight (LBW) 39(32.5%), neonatal resuscitation 33(27.5%), and prolonged rupture of membranes 21(17.5%). Conclusion: The common risk factors for neonatal sepsis in paediatric ward at Khartoum North Teaching Hospital were being delivered in hospital, history of fever or infection during pregnancy, low birth weight, neonatal resuscitation and prolonged rupture of membranes. Keywords: neonatal sepsis, risk factors, Sudan