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Paper Details

Clinical presentation of neonatal sepsis in paediatric ward at Khartoum North Teaching Hospital, Sudan

Omer Saeed Magzoub, Mohamed Awadelkrim Ahmed, Yahia Shakir Abdelgadir

Journal Title:Basic Research Journal of Medicine and Clinical Science

World Health Organization (WHO) estimates that globally there are about 5 million neonatal deaths per year. Ninety eight percent of them are occurring in developing countries in the first week of life. Infections are frequent and important cause of neonatal morbidity and mortality. Objectives: The aim of this study is to determine the common presenting symptoms and signs of neonatal sepsis in neonates admitted from emergency room to pediatrics ward in Khartoum North Teaching Hospital. Methods: A cross-sectional prospective hospital based study was conducted on 120 neonates presented with neonatal sepsis who had been admitted to Khartoum North Teaching Hospital general pediatrics ward over six months period (January 2013 to July 2013). History and physical examination were carried out and samples of blood were taken for blood culture and full blood count. Data was analyzed using the Statistical Package for Social Sciences (SPSS). Results: 120 neonates were included in this study. The sepsis was confirmed by clinical and laboratory measures. 67 (55.8%) neonates were males and 53(44.2%) were females. Early onset sepsis was detected in 79 (65.8%) neonates while late onset sepsis was detected in 41 (34.2%). Fever was the most presenting feature found in 76 (63.3%), respiratory distress present in 53 (44.2%), 48 (40%) neonates were lethargic, 47 (39.2%) had impaired feeding, and 39 (32.5%) had refusal of feeding. 38 (31.7%) neonates had neonatal jaundice and Moro reflex was absent in 25 (20.8%). Conclusion: The common presenting features of neonates with neonatal sepsis in the paediatric ward at Khartoum North Teaching Hospital were being fever, respiratory distress, lethargy, impaired or refusal of feeding, jaundice, absent Moro reflex, hypothermia, convulsions bleeding disorder and bulging fontanel. Keywords: neonatal sepsis, clinical presentation, Sudan