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Paper Details


*Dr.Deepshikha, Dr.B.M.Singh, Dr.P.S.Upadhyay

Journal Title:World Journal of Pharmaceutical Research

Respiratory infections are major cause of morbidity and mortality in children. Cough being its commonest manifestation calls for a medicine, which is efficacious, palatable and free of side effects with suitable mode of administration. Vyaghri Haritaki, a classical formulation in Bhaishajya Ratnavali, is an Avaleha (electuary), palatable and can be licked by children having soothing effect on throat. Therefore, a study was planned to evaluate its effect on Kasa (cough) due to three doshas. Children, aged 1 to 12 years, suffering from cough due to various etiologies were registered and categorized under three groups: group-1, 2 and 3 namely Vataja, Pittaja and Kaphaja kasa and drug was given in dose of 150 mg/kg/dose, 6 hourly for seven days. Two follow-ups were made after two and seven days respectively after registration. Hb, TLC, DLC, ESR, AEC, Throat-C & S, Urine-R&M, XRay chest PA view and Mantoux test were advised. Improvement was assessed on basis of scoring table present grades for symptoms in increasing order of severity. After statistical analysis, which was done by SPSS 16 software, suggest that however, Vyaghri Haritaki is effective in all three types of Kasa but shows better effect on Vataja kasa. The trial drug has no significant side effects and no significant effect on Hb%, TLC, DLC and ESR.