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Paper Details

Gardners Syndrome - A Case Report

Jay C Shah, Navin S Shah, Parshwa N.Shah.

Journal Title:Advances in Human Biology

Background: Gardners syndrome, a hereditary dominant condition, comprises of multiple osteomas, cutaneous and soft tissue tumors and polyposis coli. In 1951, Gardner reported the association between surface tumors and colonic polyps that are prone to malignant degeneration. It follows dominant hereditary pattern of multiple osteoma associated with colonic polyposis. The most commonly affected bones are the mandible and maxilla, followed by the frontal, sphenoid and ethmoid bones. The most common cutaneous finding in patients with Gardners syndrome is epidermoid cysts, which tend to be numerous and are present in the multiple forms in 50 65% of the patients.