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Paper Details

Dental Stem Cells and their Applications in Regenerative Medicine-A Review

Neelampari Parikh, Zankhana Vyas, Gunjan Dave.

Journal Title:Advances in Human Biology

Among the types of adult stem cells, those derived from tooth structures have been receiving the attention of researchers over the past decade and inspiring hope for practical applications in the future. Dental stem cells are a valuable source of stem cells and are found in teeth with healthy pulp Till date five different human dental stem cells have been isolated and characterized: Dental Pulp Stem Cells (DPSCs), Stem Cells From Exfoliated Deciduous Teeth (SHED), Periodontal Ligament Stem Cells (PDLSCs), Stem Cells From Apical Papilla (SCAP) and Dental Follicle Progenitor Cells (DFPCs). The discovery of dental stem cells and recent advances in cellular and molecular biology have led to the development of novel therapeutic strategies that aim at the regeneration of oral tissues that were injured by disease or trauma. Dental Stem cells research has given newer conceptual approach to therapy of various diseases named regenerative dentistry and it will have its place in the clinical practice of dentistry in the future. This review, discusses the types of dental stem cells, their banking and their possible application in treatment of diseases in future.