Evaluation of antiurolithiatic activity of Chlorophytum borivilianum extract using experimental animals
Timir Patel, Samir Shah and Jigar Patel
Journal Title:International Journal of Ayurveda and Pharmaceutical Chemistry
Urolithiasis, the most painful urologic disorder, refers to calculi or stone formation in the kidneys, ureter, and urinary tract due to imbalance between promoters and inhibitors of crystallization in urine. The worldwide incidence of urolithiasis is quite high and in spite of tremendous advances in the field of medicine there is no truly satisfactory mode of treatment available for treating renal calculi. For the management of urolithiasis, combination of surgical and medical approach using percutaneous nephrolithotomy (PCNL), extracorporeal shock wave lithotripsy (ESWL) and antibiotics are employed. But these treatment causes undesirable side effects such as traumatic effects, residual stone fragments persisted, infection, acute renal injury, a decrease in renal function, hemorrhage and hypertension Ayurveda, an indigenous system of Indian medicine, offers vast scope for the successful treatment of urolithiasis. In Indian traditional system of medicine, Ayurveda, many plants including Chlorophytum borivilianum has been claimed to be useful in of urinary tract infections and in kidney and bladder stones. In light of above findings our aim of present study was to evaluate the antiurolithiatic activity of Chlorophytum borivilianum extract (CBE) using experimental animals.