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Paper Details

Haematological pictures in full term new born children in Sudan

Sana E. Abdalla

Journal Title:Basic Research Journal of Medicine and Clinical Science

Background Anemia can occur when red blood cells are broken down too rapidly, too much blood is lost, or the bone marrow does not produce enough red blood cells. Normally, the bone marrow does not produce new red blood cells between birth and 3 or 4 weeks of age, causing a slow drop in the red blood cell count (called physiologic anemia) over the first 2 to 3 months of life. Very premature newborns have a slightly greater drop in red blood cell count. More severe anemia can occur when red blood cells are broken down too rapidly, a lot of blood is taken from preterm infants for blood tests, too much blood is lost during labor or delivery or the bone marrow does not produce blood cells. (Arthur E., et al 2009) The aim of this study are to measure Hb level, RBCs indices, serum iron, total iron binding capacity and serum ferritin in newborns at the time of delivery. Methods: 80 blood samples were collected from new born cord blood, complete blood count was measure using Sysmex Kx-21. Serum iron and total iron binding capacity (TIBC) were measured by an automatic instrument (BTS- 370 Plus), which performs spectrometric measurements. Serum ferritin was estimated by ELIZA technique. Results: this study showed that 18 (22.5%) babies had low Haemoglobin level, while 62 (77%) had normal level, 70 (87.5%) had normal MCV, while 10 (12.5%) had low MCV, 79(98.7%) had normal MCH, while 1(1.3%) had low MCH while all studied babies (80) had normal MCHC. Eight (10%) babies had low S. ferritin, while 69 (86.3%) babies had normal S. ferritin, and 3 (3.7%) babies had high S. Ferritin while four (5%) babies had low S. iron, 54(67.5%) babies had normal S. iron and 18(22.5%) had high S. iron. TIBC showed that 5(6.3%) babies had low TIBC, while 67(83.7%) had normal TIBC and 8(10%) babies had high TIBC. Conclusion: This study concluded that anaemia in newborn babies is not uncommon and early cord clamping should always be taken in to consideration, if other causes could not be found. Keywords: Haemoglobin, indices, iron, ferritin.