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Paper Details

Determination of Free Radical Scavenging Activity of Emblicaofficinalis Gaertn., Terminaliachebula Retz. And TerminaliabelericaRoxb.

Samiksha P. Dandekar and Dayanand P. Gogle

Journal Title:International Journal of Ayurveda and Pharmaceutical Chemistry

The present paper reports about the free radical scavenging activity of Emblicaofficinalis, Terminaliachebulaand Terminaliabelerica. The fruits of the above mentioned plants were used in the present study. The study attempts to focus on the antioxidant potential of the selected plant materials. We have undertaken this study by using the most reliable 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging method followed by the Hydroxyl radical scavenging method. The highest DPPH scavenging activity as per the IC50 values was found to be in Emblicaofficinalis (51.00 ± 1.42µg/ml) while Terminaliachebula and Terminaliabelerica showed (115.29 ± 1.86 µg/ml) and (165.29 ± 2.94 µg/ml), respectively. The highest Hydroxyl radical scavenging activity was found in Emblicaofficinalis (10.04 ± 2.92 µg/ml) while Terminaliachebula and Terminaliabelerica showed (39.65 ± 3.36 µg/ml) and (47.36 ± 2.08 µg/ml), respectively. Among all the plants studied, Emblicaofficinalis was found to be the best one with lowest IC50 values in DPPH method as well as Hydroxyl radical method, thus indicating highest free radical scavenging activity. Hence, Emblicaofficinalispossess more antioxidant potential as compared to the other two plant materials.