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Paper Details

Nasya karma (Intranasal therapy); An Alternative Route of Drug Administration into the Brain

Sheetal Asutkar, Yogita Bende, Veena Himanshu Sharma, Varsha P.Jadhao, Vasudha G.Asutkar and Chetan Gulhane

Journal Title:International Journal of Ayurveda and Pharmaceutical Chemistry

Ayurveda is the ancient system of Indian medicine in which the importance of both prevention and cure are highlighted. As per the Ayurvedic texts, The tridoshas are the main causative factors in the pathogenesis of any disease. Specific management for individual doshas have been elaborated in all Ayurvedic texts. In Ayurveda, a special procedure called Nasya karma has been mentioned. It is an alternative route of drug administration for most of the drugs that act on brain. Nasya is given in the form of oil, ghee, smoke, powder and herbal juice depending upon the nature of disease. Pharmacokinetics and pharmacodynamics of Nasya drugs and the connection of nose with brain is explained in the Ayurvedic classics. Nasya karma provides an alternative route to drug delivery to the brain with safe and efficacious formulations for simple, painless and long‐term therapy.