Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria
Adamu, U.; Yusha’u, M.; Usman, A. D.; Abdulhadi, S.K.
Journal Title:Novel Research in Microbiology Journal
This study was designed to determine the antibiotic resistance pattern of Salmonella spp. isolated from
clinical samples of symptomatic and asymptomatic typhoid patients, selected from some hospitals in Jigawa State,
Nigeria. Four hundred bacterial isolates were recovered from these samples, were identified as; Salmonella
typhimurium, S. enteritidis, S. typhi, S. paratyphi A, and S. paratyphi B using microgen biochemical system,
according to the standard techniques. The antibiogram of all these Salmonella spp. were carried out using
standard oxoid disc of different antibiotics. Double disc diffusion technique was employed to determine the
isolates’ capacity to produce β-lactamase. Results showed 5(1.25%), 0(0.0%), 0(0.0%) of the samples collected
were positive for extended spectrum β-lactamases (ESBL), AmpC β-lactamase, and Metallo β-lactamases (MBL),
respectively. The antibiogram profile of the isolates showed that 100% of these isolates are susceptible to
Imipenem, only 3% exhibited resistance to ceftriaxone, whereas 7% demonstrated resistance to ciprofloxacin. To
the best of our knowledge, this the first study of this kind in the Jigawa state, especially on these Salmonella spp.
The study concluded that β-lactamases with the capacity of conferring multidrug resistance were recorded in
Salmonella spp. isolated from patients in several hospitals of Jigawa State, Nigeria.