Clinical Study of Sarivadi Lepa and Gunja Taila in the Management of Migraine
Journal Title:International Journal of Ayurveda and Pharmaceutical Chemistry
Migraine is a complex neurological disorder which affects more than 10% of people worldwide. The clinical presentation of migraine varies from patient to patient and even in the same patient from time to time and exact pathophysiology of migraine is not known though unifying theory is postulated. Therefore, one of the aims of the present study is to look for the pathophysiological sequence of the disease. Moreover, no standard treatment is available that is common for all migraine patients. Many migraine patients self-diagnose and self-medicate themselves using over-the–counter analgesics. Many allopathic drugs are used that only provide symptomatic relief to the patient and have irreversible side-effects. Moreover, migraine surgery is a field which is still under its very initial stages. Therefore, to eradicate the problem of migraine and to test the efficacy of Ayurvedic formulations in the management of migraine, Sarivadilepa and Gunjataila have been selected from ayurvedic texts which are mentioned for the treatment of migraine in the present clinical study. Results regarding pathophysiology of migraine showed that both vascular and neural factors are responsible for migraine. Both the drugs selected for present clinical study will show suppra additive potentiated synergistic effect which will act as an important hallmark for curing migraine. Thus the present clinical study is valuable to evaluate safe and effective drug for treating the migraine which is a major health hazard in the present modern era.