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Invitro Cytotoxicity and Glucose Uptake Activity of Mushroom Pleurotus Eous in Methanol Extract Using L-6 Cell Line

K Shoba1 and S Krishnakumari2 *

Journal Title:Medical & Clinical Research
Abstract


The aim of the present study is to evaluate the cytotoxicity and glucose uptake activity of methanolic extract of pleurotus eous mushroom using L6 cell lines. An MTT assay is a colorimetric assay based on assessing the cell metabolic activityThe results showed that the extracts did not confer any cytotoxicity. The effects were observed in treated cells up to 6.25 mg/ml extract as measured with MTT. Also the mushroom extracts shows better glucose uptake potential. The results were compared with Insulin a standard antidiabetic drug. Insulin enhance the glucose uptake upto 97.8%. The L6 cell lines enhance the glucose uptake by 57.4% at 65µg concentration.

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