The Role of Genetics Mutation in Gene Tgm5 in Induce Acral Peeling Skin Syndrome
Shahin Asadi1 *, Hossein Amjadi2 and Mahsa Jamali2
Journal Title:Medical & Clinical Research
APS syndrome is a skin-related genetic disorder characterized by painless skin lesions from the upper layer of the skin. In addition to the above, sometimes peeling of the skin in the arms and legs also occurs. Skin peeling usually appears at birth, but can begin in childhood or later in life. APS syndrome is caused by the mutation of the TGM5 gene, which is based on the long arm of chromosome 15 as 15q15.2.