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Paper Details

MicroRNAs: Small RNAs, Big IMPACT!! A short commentary on miRNAs with special reference to cancers

Kanwal Tariq

Journal Title:Escalating Research
Abstract


The human genome is approximately 3 billion base pairs (bp) in size whereas every human contain two sets of this genome in most of their body cells, hence 6 billion base pairs. The Human Genome Project revealed that there are around 20,000-25,000 protein coding genes which relate to only 1.5% of the genome. The rest of the DNA, previously called junk DNA, is now known to play important part in gene expression. Some of this also code for non-coding RNA molecules which are important for regulation of the function of several genes in normal as well as diseased conditions. These include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), small interfering RNAs (siRNAs), and many others.

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