SPECTROPHOTOMETRIC DETERMINATION OF CEFADROXIL WITH 2, 3 - DICHLORO-5, 6 DICYANO-1, 4-BENZOQUINONE
Journal Title:World Journal of Pharmaceutical Research
The reaction between Cefadroxil and 2,3 - dichloro 5,6-dicyaxo-1,4-benzoquinona (DDQ) in the presence of chloroform was investigated by spectrophoto metric method were proposed the determination was
based on the formation of a charge transfer complex of drug solution with DDQ-Chloroform Mixture. The Orange coloured product under standardized conditions is scanned over the range 400-575mm. The
calibration curve for the determination of drug, constructed by recording absorbance. Results of analysis of this method was validated statistically evaluated.