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Paper Details

ANTIFUNGAL ACTIVITY OF BURSERA PENCILLATA LEAF EXTRACT ON DERMATOPHYTES

Ashok. T* Madhuri. N,Sravanthi.P , Shilpa Vemula

Journal Title:World Journal of Pharmaceutical Research
Abstract


To evaluate the in v i t ro ant ifungal act ivit y of Bursera pencillata leaf extract s and fractions on t he clinical isolat es of der mat ophyt ic fungi like Tric hophyt on ment agr ophytes, Tri chophyton rubrum, Mi crosporum cani s, Mi crosporum gypseum and Epidermophyton floccosum. The minimum inhibitory concentrati on (MIC) and minimum fungici dal concentrati on (MFC) of various extracts and fract ions of the leaves of Bursera pencillata were measured using method of Nat iona l Commit tee for Clinical Laborator y Standards ( NCCLS). Bursera pencillata leaf extracts and fractions were found to have fungicida l activity against various clinical isolates of dermatophyti c fungi . The MIC and MFC was found to be high in water and ethyl alcohol extracts and methanol fractions (200 g /mL) against dermatophytic fungi studi ed. Bursera pencillata l eaf extracts significantly inhibits the growth of all dermatophyti c fungi studi ed. If this activity is confirmed by in vivo studi es and if the compound is isolated and i denti fied, i t could be a remedy for dermatophytosis

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