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Paper Details

EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF SUDANESE HONEY AGAINST TYPHOIDAL& NON-TYPHOIDAL SALMONELLAE

Eljack M S*, Kafi S K

Journal Title:World Journal of Pharmaceutical Research
Abstract


Back ground: Typhoid fever remains a serious public health problem throughout the world, with an estimated 1633 million cases and 500 000 to 600 000 deaths annually. Honey has been used by humans to treat a variety of ailments, from gastric disturbances to ulcers, wounds and burns, through ingestion or topical application, but only recently have the antiseptic and antibacterial properties of honey been chemically explained. Few studies that have studied the antibacterial activity of Sudanese honey were reported but none of them evaluated the antibacterial activity of honey on certain Salmonella species. This study was therefore performed to study the effect of three types of honey on selected Salmonella species. Materials and methods: the antibacterial activity of three mono floral Sudanese honey (Acacia, Sidr and Sunflower honey) were evaluated using agar well diffusion susceptibility method in different concentrations(undiluted honey,75%, 50% and 25%v/v) against nineteen salmonella isolates in addition to reference strain (S.typhimurium NCTC12023, ATCC14028) compared to the commercial antibiotics (ciprofloxacin). Results: All clinical isolates and the reference strain were observed to be susceptible to undiluted honey, 75% and 50% v/v dilutions of the three types of honey used according to Clinical and Laboratory Standards Institute (CLSI) formerly NCCLS. Variations in susceptibility of some isolates were observed at dilution of 25%v/v of the three honey types.

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