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Paper Details

The Cell Wall of Mycobacteria

The Cell Wall of Mycobacteria

Dr Manaswini Das

Journal Title:
Abstract


The cell wall of mycobacteria deserves special mention due to its unique structure among prokaryotes and a major determinant of virulence. It is composed of peptidoglycan and more than 60% of the cell wall has complex lipids. Mycolic acids are unique ?-branched lipids found in other genera like Nocardia and Corynebacteria. The unique cell wall is responsible for impermeability to stains and dyes, resistance to many antibiotics, killing by acidic and alkaline compounds, resistance to osmotic lysis by complement deposition and survival inside macrophages.

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