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Paper Details

Intradermal Antirabies Vaccination: A Technique to Increase Compliance

Intradermal Antirabies Vaccination: A Technique to Increase Compliance

Dr. Rohi KR, Dr. Mankeshwar R

Journal Title:
Abstract


Background: Compliance to post-exposure vaccination is crucial to achieve optimum level of antibody titers. The present study was planned to assess the compliance of 4 dose intradermal regimen over 5 dose intramuscular regimen. Objective: To study adherence of patients to 4 dose regimen. Methods: Hospital record based study. Patients who attended Antirabies clinic from Jan 2010 to Dec 2010 were studied. 2051 patients who were given Inj. PCECV by intradermal route formed the study group. Pearson’s Chi square test was used as a test of significance. Result: 2051 patients were studied.1741 (84.9%) patients were male.1907 (92.9%) were dog bites. 1277(62.3%) were stray dog bites. 1516 (58.0%) were class III dog bites.1313 (68.2%) were non-observable dog bites.1711 (88.7%) were provoked dog bites. Most common site of dog bite was over the lower limb i.e.1350 (70.2%).1255 (65.3%) patients completed the 4 dose regimen. This in stark contrast to previous evidence from our centre in which a compliance of 40.2% to the intramuscular regimen was evident. (Pearson X2 = 180.94, df= 1, p< 0.0001).Conclusion: It was observed intradermal regimen had more patient adherence compared to intramuscular regimen.

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