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Paper Details

OGTT A PRELIMINARY APPROACH TO DETECT IMPAIRED GLUCOSE TOLERANCE IN CHRONIC PANCREATIC DISORDERS

Dr.C.V.Sarada, Dr. Sujatha Rani Akuri*

Journal Title:World Journal of Pharmaceutical Research
Abstract


Chronic pancreatic disorder patients are more prone for diabetes. To rule the prediabetes condition in chronic pancreatic disorder patients we do various tests for confirmation like Serum insulin test, OGTT, Serum peptide tests. OGTT test used for to rule out diabetes in normal condition. In this present study we took 30 chronic pancreatic disorder patients and 20 healthy volunteers and tested OGTT levels both fasting and after glucose load. From this study we came to know that fasting OGTT levels are almost same in both the groups but the 2nd hour levels are high in the case group. The primary application of OGTT is after glucose loading. The high levels of OGTT after 2nd hour may be due to decreased insulin production or due to insulin resistance. The high levels of the post glucose load glucose levels in cases indicate irregularity in glucose metabolism. This represents the patients with Chronic Pancreatic disorders have a chance to develop Diabetes Mellitus II in future.

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