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Paper Details

SCREENING OF PHYTOCONSTITUENTS ACTIVITY AND ANTIMICROBIAL EFFICACY OF DIFFERENT EXTRACTS OF GNAPHALIUM POLYCAULON

K. Shanmugapriya and Dr.Tha.Thayumanavan*

Journal Title:World Journal of Pharmaceutical Research
Abstract


The present study comprises the efficiency of phytochemical and antimicrobial activity of aqueous, ethanol and hexane extracts of leaf, stem and flower of Gnaphalium polycaulon. The qualitative phytochemical investigation was carry out by identifying the presence of major phytochemicals using standard procedure. The selected plant used in traditional Indian medicine was examined against human pathogenic Gram positive and Gram negative bacteria and fungus using the agar well diffusion method against various diseases causing drug resistant microorganisms. Based on the results obtained, the phytochemical screening relieved that the leaf and stem were rich in alkaloids, flavonoids, tannins, carbohydrates, proteins, tannins, Alkaloids, amino acids, fatty acids, glycosides, steroids and saponins, than flower extract and confirmed the presence of all Phytoconstituents in selected plant. The antimicrobial activity of various extracts of G. polycaulon showed varied levels of antimicrobial activity against the studied bacterial and fungal pathogens. Result findings provided evidence that crude organic solvent extracts of selected plants contain medicinally important phytochemical compounds and their use in the traditional herbal medicines. Therefore, further studies on this medicinal plant will be widely used in number of pharmacological actions for the treatment of different diseases.

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